Cosmetic efficacy testing provides scientific evidence that skin care, hair care, scalp care, sunscreen, and makeup products deliver their claimed benefits. Brands use cosmetic claim substantiation studies to support marketing claims, comply with cosmetic regulations, and demonstrate measurable product performance.
Whether for skin care, hair care, or personal care products, companies must demonstrate that their formulations deliver visible, measurable, and reliable results. Robust efficacy testing helps support product claims, build consumer trust, and meet regulatory expectations across global markets
CIRS offers comprehensive cosmetic efficacy testing services, including in vivo studies, in vitro testing, consumer perception research, and clinical evaluations to support claim substantiation and global regulatory compliance.
CIRS Cosmetic Efficacy Testing at a Glance
- Cosmetic Claim Substantiation Studies;
- In Vivo and In Vitro Efficacy Testing;
- Skin Care, Hair Care, Scalp Care, Makeup, and Sunscreen Evaluations;
- Consumer Perception and Sensory Studies;
- Regulatory Support for Global Markets Including EU, UK, US, China, and South Korea;
- Database of 10,000+ Volunteers; and
- CMA & CNAS-accredited Laboratories, Operating to ISO 17025 & ISO 17020 standards.
Ensure Scientific Substantiation of Cosmetic Claims
Cosmetic claim substantiation requires reliable scientific evidence demonstrating that a product delivers its advertised benefits. CIRS conducts in vivo studies, in vitro testing, instrumental assessments, and consumer perception studies to support cosmetic claims across skin care, hair care, scalp care, sun protection, and makeup products.
Skin Care
CIRS provides all skin care testing services to evaluate product efficacy, safety, and performance across a wide range of skin concerns, ensuring compliance with global cosmetic regulatory standards.
Testing Items
| In-vivo | ●Hydration ●Barrier Repairing ●Skin Nourishment ●Anti-wrinkle ●Firmness & Elasticity ●Acne Control ●Oil Control ●Soothing ● Brightening ●Exfoliating |
| In-vitro | ●Moisturizing ●Skin Repair ●Soothing/Anti-stress ●Anti-ageing ●Oil/Acne Control ●Brightening/ Skin Radiance |
To learn more details about our skin care efficacy evaluation services, please click here.
Hair Care
CIRS provides hair care efficacy and damage evaluation testing, using six key damage evaluation models – heat, chemical, physical, air pollution damage, UV, sea/pool water exposure – applied to 3D human hair tresses.
Testing Items
| Physical Performance | Chemical Composition | Microscopic & Structural Analysis |
●Dry and wet combing performance ●Frictional properties ●Tensile strength and fiber resilience ●Gloss and shine assessment ●Surface hydrophilicity ●Hair breakage analysis (number of broken fibers) ●Spilt end evaluation ●Anti-frizz and anti-static performance ●Curl retention testing ●Color durability assessment ●Hair fiber fineness | ●α- keratin content (DSC) ●Lipid content (GC-MS & LC-MS/MS) ●Amino acid profile (HPLC) ●Lipid peroxidation (UV analysis) ●Protein loss and dissolution (UV) ●Moisture content (TGA) ●Disulfide bond integrity (Raman Spectroscopy) ●Fragrance longevity evaluation | ●Cuticle repair and surface texture analysis ●Cross-sectional structure analysis ●Hair fiber morphology comparison ●Protein penetration studies ●Spectroscopic characterization ●Hair integrity assessment ●Core penetration analysis ●Dye penetration testing ●Hair porosity and void ratio evaluation |
To learn more details about our hair care efficacy evaluation services, please click here.
Scalp Care
CIRS provides clinical scalp care testing services to evaluate product efficacy across key concerns, including dandruff, scalp hydration, barrier repair, and hair loss.
Testing Items
| In-vivo | ●Dandruff (Professional Analysis) ●Scalp Repair ●Scalp Hydration ●Anti-Hair Loss Efficacy |
Learn more details about our scalp care efficacy evaluation services.
Sun Protection
CIRS provides clinical sun protection testing services to evaluate sunscreen efficacy and ensure compliance with global regulatory standards for UV protection claims.
Testing Items
| In-vivo | ●SPF (UVB) Testing ●UVA Protection Testing ●Water Resistance (40 Minutes) ●Very Water Resistance (80 Minutes) |
Explore our SPF and sun protection testing services.
Makeup
CIRS provides clinical makeup testing services to evaluate product performance, durability, and consumer-relevant outcomes under real-use conditions.
Testing Items
| In-vivo | ●Long Lasting Performance ●Concealing Efficacy ●Gloss & Shine ●Even Skin Tone ●Makeup Removal ●Waterproof Performance ●Sweat Resistance ●Hybrid Makeup (Makeup + Skin care) |
View our makeup testing services.
Consumer Research
CIRS conducts consumer perception and use testing to evaluate real-world product performance and user experience, supporting marketing claims and product positioning.
Testing Items
●Consumer In Use Study ●Final Consumer Study ●Sensory Evaluation
Find out more about our consumer research services.
Extensive Database of Volunteers
Supported by dedicated system software and a professional operations team, we maintain and continuously update a database of over 10,000 volunteers.
We recruit targeted volunteers through different channels:
- Partnering with universities to secure young participants for skin care studies, including those with acne or student-specific skin concerns.
- Working with hospitals to source volunteers with special skin conditions such as chronic eczema and rosacea.
- Collaborating with aesthetic medical institutions to recruit participants for trials that involve combined aesthetic treatments.
We can grow and customize the volunteer pool based on specific customer needs.

Why Choose Us?
Global Network: Subsidiaries in major cosmetic markets, supporting regulatory compliance in China, South Korea, the EU, the UK, the US, and beyond.
Expert Team & Accredited Labs: Our highly qualified scientists, toxicologists, and regulatory specialists are supported by CMA & CNAS-accredited laboratories, operating to ISO 17025 & 17020 standards.
Proven Track Record: Thousands of successful cosmetic testing and regulatory compliance projects delivered for global brands.
Comprehensive Solutions: End-to-end cosmetic testing and regulatory consulting services, from assessment to reporting.
About CIRS
Established in 2007, the CIRS Group is a leading product safety and regulatory consulting firm. CIRS has branch offices in the Republic of Ireland, South Korea, the United States, the United Kingdom, Japan and China. CIRS Group utilizes its technical expertise, various resources, and international network to provide one-stop compliance services from regulatory compliance, laboratory testing, R&D to data services across multiple industries. This includes chemicals, cosmetics, food and food beverages, medical devices, agrochemical products, disinfectants, and consumer goods. It helps clients gain a competitive advantage by reducing business risks associated with regulatory affairs.
The CIRS cosmetic team provides expert support to ensure that cosmetic products meet stringent global cosmetic regulations and safety standards. With deep expertise in cosmetic regulatory compliance and safety evaluations, our team enables brands to bring products to market efficiently and with confidence.
We offer comprehensive, lifecycle-based solutions for personal care products, from early-stage cosmetic ingredient development through to final product registration. Our services include:
- Cosmetic ingredient development and regulatory strategy,
- Physical/chemical and analytical tests,
- Toxicological tests (in vivo & in vitro),
- Efficacy and claim substantiation studies (in vivo & in vitro), and
- Ingredient and product registration across global markets.
