China CFSA Recommend Not Granting Approval for L-Ergothioneine and Brazzein

Recently, China's National Health Commission (NHC) issued notifications regarding the approval and review of “Three new foods” (new food raw materials, new food additives, and new food-related products). The notifications included:

Thirty extension notices; and
Seven notifications of review opinions.

China,Food,Three,New,Additive,Material

Details are as follows:

Extension notice (requires supplementary materials following the technical review by China National Center for Food Safety Risk Assessment (CFSA))

New food raw materials

SN	Date	File Number	Product Name
1	2025-08-06	衛食新申字(2021)第0010號	D-psicose
2	2025-08-06	衛食新申字(2023)第0009號	D-psicose
3	2025-08-06	衛食新申字(2025)第0012號	L-Ergothioneine
4	2025-08-06	衛食新申字(2025)第0028號	L-Ergothioneine
5	2025-08-06	衛食新申字(2025)第0024號	N-Acetylneuraminic acid (Neu5Ac)
6	2025-08-06	衛食新申字(2022)第0014號	Bifidobacterium animalis subsp. lactis CP-9
7	2025-08-06	衛食新申字(2023)第0007號	Bifidobacterium animalis subsp. lactis XLTG11
8	2025-08-06	衛食新申字(2025)第0031號	Fermented mycelial protein (Fusarium venenatum)
9	2025-08-06	衛食新申字(2025)第0027號	Krill oil
10	2025-08-06	衛食新申字(2024)第0009號	L-Ergothioneine
11	2025-08-06	衛食新申字(2025)第0005號	L-Ergothioneine
12	2025-08-06	衛食新進申字(2025)第0002號	Proanthocyanidins
13	2025-08-06	衛食新申字(2025)第0019號	Extract of Cyclocarya paliurus leaves
14	2025-08-06	衛食新申字(2025)第0026號	Extract of Cyclocarya paliurus leaves
15	2025-08-06	衛食新申字(2025)第0023號	Ampelopsis grossedentata polyphenols
16	2025-08-06	衛食新進申字(2025)第0006號	Streptococcus salivarius K12
17	2025-08-06	衛食新進申字(2025)第0007號	Streptococcus salivarius M18
18	2025-08-06	衛食新進申字(2025)第0005號	Banana flower
19	2025-08-06	衛食新申字(2025)第0030號	Fermented corn extract

New food additives

SN	Date	File Number	Product Name
1	2025-08-01	衛食添新申字(2025)第0065號	2'-Fucosyllactose
2	2025-08-01	衛食添新申字(2025)第0067號	3-Fucosyllactose
3	2025-08-01	衛食添新申字(2023)第0033號	6'-Sialyllactose sodium salt
4	2025-08-01	衛食添新申字(2024)第0034號	6'-Sialyllactose sodium salt
5	2025-08-01	衛食添新申字(2025)第0063號	Calcium D-Pantothenate
6	2025-08-01	衛食添新申字(2025)第0072號	Lycopene
7	2025-08-01	衛食添新申字(2025)第0060號	Gellan gum
8	2025-08-01	衛食添新申字(2025)第0061號	Gellan gum
9	2025-08-01	衛食添新申字(2025)第0069號	Monopotassium phosphate
10	2025-08-01	衛食添新申字(2025)第0070號	Monopotassium phosphate
11	2025-08-01	衛食添新申字(2024)第0087號	Deaminase

Review opinions (CFSA recommends not granting approval after the technical review)

New food raw materials

SN	Date	File Number	Product Name
1	2025-08-05	衛食新申字(2025)第0029號	L-Ergothioneine

New food additives

SN	Date	File Number	Product Name
1	2025-08-01	衛食添新申字(2025)第0003號	2-Hydroxy-4-methoxybenzaldehyde
2	2025-08-01	衛食添新申字(2025)第0068號	Brazzein
3	2025-08-01	衛食添新申字(2025)第0066號	Tomato lycopene
4	2025-08-01	衛食添新申字(2025)第0064號	Enzymatically synthesized ascorbyl palmitate
5	2025-08-01	衛食添新申字(2025)第0071號	Enzyme-modified steviol glycosides
6	2025-08-01	衛食添新申字(2025)第0062號	Invertase

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Further Information

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